United States securities and exchange commission logo June 24, 2024 Brent Pfeiffenberger Chief Executive Officer Century Therapeutics, Inc. 25 North 38th Street, 11th Floor Philadelphia, PA 19104 Re: Century Therapeutics, Inc. Registration Statement on Form S-3 Filed June 18, 2024 File No. 333-280310 Dear Brent Pfeiffenberger: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Doris Stacey Gama at 202-551-3188 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Jennifer Porter, Esq.